Bulk Food Grade 99% D-Mannitol Powder Supplier in China

D-Mannitol Powder is available in three main grades: food grade for sweetener use, oral pharmaceutical excipient grade, and injectable pharmaceutical grade. All three use the same molecular formula, C6H14O6, but they differ in quality standards, impurity limits, microbial controls, production environment, particle size, crystal form, documentation, intended use, and price.

Food Grade D-Mannitol for Sweetener Applications

BSH Ingredients supplies Food Grade 99% D-Mannitol Powder for sweetener and food-processing applications. This grade is produced according to GB 1886.177-2016, the Chinese food-additive standard for D-Mannitol, and is used under the applicable requirements of GB 2760-2024.

Food-grade material is commonly used in sugar-free candy, chewing gum, mint tablets, compressed candy, chocolate, baked products, powdered drinks, ice cream, meal replacements, functional foods, and dietary supplements. It provides about 57% to 72% of the sweetness of sucrose, depending on the formulation. It also offers a cooling mouthfeel, low moisture absorption, good flow, and useful bulk in reduced-sugar products.

The food-grade specification generally requires a dry-basis assay of at least 98.0%. Typical limits may include total heavy metals of no more than 10 ppm, lead of no more than 2 ppm, and arsenic of no more than 2 ppm, subject to the adopted standard and buyer requirements. Routine food-grade testing covers identity, assay, reducing sugars, sorbitol, moisture, ash, pH, optical rotation, chlorides, sulphates, nickel, lead, arsenic, and standard food microbiology. It does not include the sterility, pyrogen, or bacterial endotoxin controls required for injectable products.

Oral Pharmaceutical Excipient Grade

Oral pharmaceutical excipient grade is intended for tablets, chewable tablets, lozenges, capsules, and oral powder formulations. In China, this grade may be tested according to the mannitol excipient monograph in Chinese Pharmacopoeia 2025, Volume IV.

This grade usually has a dry-basis assay of at least 99.0% and tighter limits for reducing sugars, sorbitol, related isomers, nickel residues, and microbial counts. A common microbial target is a total aerobic count of no more than 100 CFU/g, with specified pathogens absent, depending on the pharmacopoeial monograph and dosage form.

Oral excipient grades may also provide tighter particle-size control and improved compression performance. They are suited to pharmaceutical production, but their higher cost is often unnecessary for standard food sweetener applications.

Injectable Pharmaceutical Grade

Injectable pharmaceutical grade is used in mannitol infusion, sterile IV preparations, injectable formulations, and freeze-dried biologic products. In China, it may be controlled under Chinese Pharmacopoeia 2025, Volume II as a pharmaceutical raw material.

This grade often requires an assay of at least 99.5%, tighter control of related substances, conductivity, organic impurities, microorganisms, sterility, and bacterial endotoxins. A typical endotoxin limit may be 0.08 EU/mg or lower, depending on the finished product and pharmacopoeial requirement.

Production must take place under a pharmaceutical GMP system with suitable cleanroom controls. Export projects may also require DMF, CEP, or other drug-registration documents. Food-grade D-Mannitol from BSH Ingredients is not intended for injections, IV solutions, or sterile pharmaceutical use.

Particle Size and Crystal Form

Particle size is one of the most important purchasing factors for sweetener applications. BSH Ingredients can supply or discuss different mesh ranges according to the required flow, dissolution rate, mouthfeel, and processing method.

20 to 40 mesh coarse crystals are suitable for chewing gum, hard candy, and mint products. They provide good flow, a clear cooling sensation, and lower caking risk.

40 to 80 mesh medium particles are often used in sugar-free chocolate, bakery mixes, nutrition powders, and general dry blends. This range offers a practical balance between flow and mixing.

100 to 200 mesh fine powder is better suited to powdered beverages, compressed candy, meal-replacement shakes, and fine supplement blends. It disperses faster and provides a smoother mouthfeel.

Special pharmaceutical grades may include amorphous mannitol for freeze-dried products or 300 to 500 mesh micronized powder for certain tablets and lozenges. These forms are rarely needed in food manufacturing.

How to Choose the Right Grade

Food manufacturers, sweetener distributors, and confectionery producers should normally select food-grade D-Mannitol that complies with the applicable food-additive standard. For sugar-free candy and chewing gum, 20 to 80 mesh material usually provides the best balance of flow, cooling effect, and cost.

Manufacturers of powdered drinks, compressed candy, and nutrition products may prefer 100 to 200 mesh powder for faster dispersion and a finer texture. There is usually no need to purchase pharmaceutical or injectable grade for ordinary food applications.

Before ordering, buyers should confirm the assay, particle size, heavy-metal limits, microbiological requirements, packaging, intended application, and destination-market standard. BSH Ingredients supplies Food Grade 99% D-Mannitol Powder in 25 kg bags with a PE inner liner, supported by a batch COA, product specification, available Halal and Kosher documents, third-party testing, samples, and international shipping service.